| NL Injuries | | |
| Arizona Diamondbacks |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| Brandon Webb | SP | 03/05/2010 | is questionable for the start of the season | Questionable | right shoulder surgery |
| |
| Atlanta Braves |
| Fielders | Pos. | Date | Details | Status | Injury |
| Diory Hernandez | IF | 02/26/2010 | is out indefinitely | Out | left shoulder surgery |
| Pitcher | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| |
| Chicago Cubs |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| Angel Guzman | RP | 03/07/2010 | is out indefinitely | Out | to undergo right shoulder surgery |
| Ted Lilly | SP | 02/09/2010 | is expected to miss the start of the season | Out | left shoulder surgery |
| |
| Cincinnati Reds |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| Edinson Volquez | SP | 02/22/2010 | is on the 60-day disabled list | Out | right elbow surgery |
| |
| Colorado Rockies |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| Rafael Betancourt | RP | 03/12/2010 | is questionable for the start of the season | Questionable | shoulder |
| Taylor Buchholz | RP | 02/09/2010 | is out indefinitely | Out | right elbow surgery |
| |
| Florida Marlins |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| |
| Houston Astros |
| Fielders | Pos. | Date | Details | Status | Injury |
| Lance Berkman | 1B | 03/13/2010 | is questionable for the start of the season | Questionable | arthroscopic left knee surgery |
| Pitcher | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| |
| Los Angeles Dodgers |
| Fielders | Pos. | Date | Details | Status | Injury |
| Russell Martin | C | 03/07/2010 | is expected to miss the start of the season | Out | strained right groin |
| Pitcher | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| |
| Milwaukee Brewers |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| David Riske | RP | 02/26/2010 | is doubtful for the start of the season | Doubtful | right elbow surgery |
| |
| New York Mets |
| Fielders | Pos. | Date | Details | Status | Injury |
| Carlos Beltran | CF | 02/09/2010 | will miss the start of the season | Out | arthroscopic right knee surgery |
| Jose Reyes | SS | 03/11/2010 | is expected to miss the start of the season | Out | thyroid |
| Pitcher | Pos. | Date | Details | Status | Injury |
| Kelvim Escobar | RP | 02/27/2010 | is doubtful for the start of the season | Doubtful | sore right shoulder |
| |
| Philadelphia Phillies |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| Brad Lidge | RP | 02/09/2010 | is questionable for the start of the season | Questionable | right elbow/knee surgery |
| Jamie Moyer | SP | 02/09/2010 | is doubtful for the start of the season | Doubtful | left knee/abdominal surgery |
| J.C. Romero | RP | 02/09/2010 | is questionable for the start of the season | Questionable | left elbow surgery |
| |
| Pittsburgh Pirates |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| Jose Ascanio | RP | 02/09/2010 | is out indefinitely | Out | right shoulder surgery |
| Joel Hanrahan | RP | 02/18/2010 | is doubtful for the start of the season | Doubtful | strained right elbow |
| |
| San Diego Padres |
| Fielders | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| Pitcher | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| |
| San Francisco Giants |
| Fielders | Pos. | Date | Details | Status | Injury |
| Freddy Sanchez | 2B | 02/18/2010 | is questionable for the start of the season | Questionable | right shoulder surgery |
| Pitcher | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| |
| St. Louis Cardinals |
| Fielders | Pos. | Date | Details | Status | Injury |
| Brendan Ryan | SS | 02/18/2010 | is questionable for the start of the season | Questionable | right wrist surgery |
| Pitcher | Pos. | Date | Details | Status | Injury |
| No significant injuries |
| |
| Washington Nationals |
| Fielders | Pos. | Date | Details | Status | Injury |
| Jesus Flores | C | 02/18/2010 | is questionable for the start of the season | Questionable | right shoulder surgery |
| Pitcher | Pos. | Date | Details | Status | Injury |
| Ross Detwiler | SP | 02/18/2010 | will miss the start of the season | Out | hip surgery |
| Chien-Ming Wang | SP | 02/20/2010 | will miss the start of the season | Out | right shoulder surgery |
| Jordan Zimmermann | SP | 02/19/2010 | is on the 60-day disabled list | Out | right elbow surgery |
| |
| |
Recent updates in red.
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