| AL |
|---|
| Toronto Blue Jays at New York Yankees, 1:05 pm |
| (R) Brandon Morrow (10-6) vs. (R) Ivan Nova (1-0) |
| Tampa Bay Rays at Baltimore Orioles, 7:05 pm |
| (R) Matt Garza (13-7) vs. (R) Kevin Millwood (3-14) |
| Chicago White Sox at Boston Red Sox, 7:10 pm |
| (L) John Danks (12-9) vs. (R) Clay Buchholz (15-5) |
| Detroit Tigers at Kansas City Royals, 8:10 pm |
| (R) Jeremy Bonderman (7-9) vs. (R) Zack Greinke (8-11) |
| Texas Rangers at Minnesota Twins, 8:40 pm |
| (L) Derek Holland (2-2) vs. (R) Nick Blackburn (8-8) |
| LA Angels of Anaheim at Oakland Athletics, 10:05 pm |
| (L) Scott Kazmir (8-12) vs. (L) Gio Gonzalez (12-8) |
| Cleveland Indians at Seattle Mariners, 10:10 pm |
| (R) Fausto Carmona (11-13) vs. (L) Luke French (3-4) |
| NL |
|---|
| New York Mets at Chicago Cubs, 2:20 pm |
| (R) R.A. Dickey (9-5) vs. (R) Randy Wells (6-12) |
| Washington Nationals at Pittsburgh Pirates, 7:05 pm |
| (R) Livan Hernandez (9-9) vs. (L) Zach Duke (6-12) |
| Milwaukee Brewers at Philadelphia Phillies, 7:05 pm |
| (L) Chris Capuano (2-2) vs. (L) Cole Hamels (8-10) |
| Atlanta Braves at Florida Marlins, 7:10 pm |
| (R) Kenshin Kawakami (1-9) vs. (L) Andrew Miller (0-0) |
| Cincinnati Reds at St. Louis Cardinals, 8:15 pm |
| (R) Bronson Arroyo (14-8) vs. (L) Jaime Garcia (12-6) |
| Houston Astros at Arizona Diamondbacks, 9:40 pm |
| (R) Brett Myers (10-7) vs. (R) Dan Hudson (4-1) |
| Colorado Rockies at San Diego Padres, 10:05 pm |
| (R) Aaron Cook (4-8) vs. (L) Cory Luebke (0-0) |
| San Francisco Giants at Los Angeles Dodgers, 10:10 pm |
| (L) Barry Zito (8-10) vs. (R) Chad Billingsley (10-8) |
